The vertical distribution of subseafloor archaeal communities is regarded as primarily managed by in situ situations in sediments similar to the availability of electron acceptors and donors, though sharp group shifts have additionally been noticed at lithological boundaries suggesting that at the very least a subset of vertically stratified Archaea kind a long-term genetic document of coinciding environmental situations that occurred at the time of sediment deposition. To substantiate this chance, we carried out a extremely resolved 16S rRNA gene survey of vertically stratified archaeal communities paired with paleo-oceanographic proxies in a sedimentary document from the northern Red Sea spanning the final glacial-interglacial cycle (i.e., marine isotope levels 1-6; MIS1-6).
Our outcomes present a powerful vital correlation between subseafloor archaeal communities and drastic paleodepositional changes related to glacial low vs. interglacial excessive stands (ANOSIM; R = .73; p = .001) and solely a reasonably robust correlation with lithological changes. Bathyarchaeota, Lokiarchaeota, MBGA, and DHVEG-1 had been the most ample recognized archaeal teams. Whether they represented historic cell traces from the time of deposition or migrated to the particular sedimentary horizons after deposition stays speculative. However, we present that the majority of sedimentary archaeal tetraether membrane lipids had been of allochthonous origin and never produced in situ.
Slow post-burial progress below energy-limited situations would clarify why the downcore distribution of these dominant archaeal teams nonetheless not directly reflect changes in the paleodepositional atmosphere that prevailed throughout the analyzed marine isotope levels. In addition, archaea seeded from the overlying water column similar to Thaumarchaeota and group II and III Euryarchaeota, which had been probably not have been capable of subsist after burial, had been recognized from a decrease abundance of preserved sedimentary DNA signatures, and represented direct markers of paleoenvironmental changes in the Red Sea spanning the final six marine isotope levels.
Harnessing paleo-environmental modeling and genetic information to foretell intraspecific genetic construction
Spatially express simulations of gene circulation inside advanced landscapes might assist forecast the responses of populations to international and anthropological changes. Simulating how previous local weather change formed intraspecific genetic variation can present a validation of fashions in anticipation of their use to foretell future changes. We overview simulation fashions that present inferences on inhabitants genetic construction. Existing simulation fashions usually combine advanced demographic and genetic processes however are much less centered on the panorama dynamics. In distinction to earlier approaches integrating detailed demographic and genetic processes and solely secondarily panorama dynamics, we current a mannequin primarily based on parsimonious organic mechanisms combining habitat suitability and mobile processes, relevant to advanced landscapes.
The simulation mannequin takes as enter (a) the species dispersal capacities as the principal organic parameter, (b) the species habitat suitability, and (c) the panorama construction, modulating dispersal. Our mannequin emphasizes the position of panorama options and their temporal dynamics in producing genetic differentiation amongst populations inside species. We illustrate our mannequin on caribou/reindeer populations sampled throughout the total species distribution vary in the Northern Hemisphere. We present that simulations over the previous 21 kyr predict a inhabitants genetic construction that matches empirical information. This strategy taking a look at the affect of historic panorama dynamics on intraspecific construction can be utilized to forecast inhabitants construction below local weather change eventualities and consider how species vary shifts may induce erosion of genetic variation inside species.
Bermudagrass (Cynodon dactylon Pers.) is a crucial warm-season perennial used extensively for turf, forage, soil conservation and remediation worldwide. However, restricted genomic info has hindered the software of molecular instruments in the direction of understanding genome evolution and in breeding new cultivars. We genotype a first-generation selfed inhabitants derived from the tetraploid (4x = 36) ‘A12359’ utilizing genotyping-by-sequencing. A high-density genetic map of 18 linkage teams (LGs) is constructed with 3,544 markers. Comparative genomic analyses reveal that every of 9 homeologous LG pairs of C. dactylon corresponds to at least one of the first 9 chromosomes of Oropetium thomaeum.
Phylotranscriptomics in Cucurbitaceae Reveal Multiple Whole-Genome Duplications and Key Morphological and Molecular Innovations
The capacity of climbing crops to develop upward alongside others to succeed in the cover for photosynthesis is hypothesized as a key innovation in flowering crops. Most members of the Cucurbitaceae, a household containing ∼1000 species and lots of necessary crops, are climbers and have attribute tendrils and pepo fruits. Here, we current 127 newly sequenced transcriptomes and genomes together with different datasets for a complete of 136 cucurbits representing all tribes to ascertain a strong Cucurbitaceae phylogeny containing eight extremely resolved main clades.
We analyzed whole-genome duplication, diversification dynamics, and ancestral morphologies, and located that after early genome duplication occasion(s), a burst of diversification and morphological improvements in flower, fruit, and root characters occurred below the local weather optimum in the Early Eocene. Species radiation throughout the Mid-Eocene Climatic Optimum additionally coincided with a number of morphological changes shared by 80% of cucurbits. We discovered that the cucurbit-specific tendril identification gene TEN originated from a paleo-polyploidization occasion at the origin of the household.
 VEGFR-1 / FLT-1 Antibody |
|
abx239393-100ug |
Abbexa |
100 ug |
EUR 481 |
|
|
 Anti-Flt-4 Antibody |
|
A01276-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for Flt-4 Antibody (FLT4) detection.tested for IHC, WB in Human, Mouse, Rat. |
 Rabbit Anti-human FLT-1/VEGFR-1 IgG #1, aff pure |
|
FLT11-A |
Alpha Diagnostics |
100 ul |
EUR 482 |
 Human FLT-1/VEGFR-1 Control/blocking peptide #1 |
|
FLT11-P |
Alpha Diagnostics |
100 ug |
EUR 164 |
 Mouse Monoclonal Anti-human FLT-1/VEGFR-1 IgG, aff pure |
|
FLT12-M |
Alpha Diagnostics |
100 ug |
EUR 482 |
Mouse Monoclonal Anti-human FLT-1/VEGFR-1 IgG, aff pure |
|
FLT14-M |
Alpha Diagnostics |
100 ug |
EUR 482 |
 VEGFR-2, human recombinant protein |
|
P1080-.1 |
ApexBio |
100 µg |
EUR 1929 |
|
Description: Vascular endothelial growth factor receptor 2 (VEGFR-2) belongs to the family of receptor tyrosine kinases (RTKs) and is almost exclusively restricted to endothelial cells. VEGFR-2 has a lower affinity for VEGF than the Flt-1 receptor, but a higher signaling activity |
 IgG, aff pure) Rabbit Anti-Mouse FLT-1/VEGFR-1 (279-299aa) IgG, aff pure |
|
FLT15-A |
Alpha Diagnostics |
100 ul |
EUR 482 |
 Polyclonal Goat anti-GST α-form |
|
GST-ANTI-1 |
Detroit R&D |
50 uL |
EUR 280 |
 Rabbit Anti-Mouse FLT-4/VEGFR-3 IgG #1, aff pure |
|
FLT41-A |
Alpha Diagnostics |
100 ug |
EUR 482 |
 VEGFR Tyrosine Kinase Inhibitor II |
|
C4603-1 |
ApexBio |
1 mg |
EUR 118 |
 Mouse FLT-4/VEGFR-3 Control/blocking peptide #1 |
|
FLT41-P |
Alpha Diagnostics |
100 ug |
EUR 164 |
 Anti-Flt-1 antibody |
|
STJ98080 |
St John's Laboratory |
100 µl |
EUR 234 |
|
Description: Mouse monoclonal to Flt-1. |
Anti-Flt-1 antibody |
|
STJ93093 |
St John's Laboratory |
200 µl |
EUR 197 |
|
Description: Rabbit polyclonal to Flt-1. |
Anti-Flt-1 antibody |
|
STJ93094 |
St John's Laboratory |
200 µl |
EUR 197 |
|
Description: Rabbit polyclonal to Flt-1. |
 Anti-PARP-1 Antibody |
|
A00122-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal PARP-1 Antibody. Validated in ELISA, IP, IF, WB and tested in Human, Mouse. |
 Anti-Presenilin 1 Antibody |
|
A00138-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for Presenilin 1 Antibody (PSEN1) detection. Tested with WB, IHC in Human, Mouse, Rat. |
 Anti-PAI-1 Antibody |
|
A00637-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for PAI-1 Antibody (SERPINE1) detection.tested for WB in Human, Mouse, Rat. |
 Anti-Flk-1 Antibody |
|
A00901-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for Flk-1 Antibody (KDR) detection.tested for WB in Human, Mouse. |
 Anti-EDG-1 Antibody |
|
A01502-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for EDG-1 Antibody (S1PR1) detection.tested for WB in Human, Mouse, Rat. |
 Anti-ROBO-1 Antibody |
|
A01530-1 |
BosterBio |
100ug |
EUR 455 |
|
Description: Rabbit Polyclonal ROBO-1 Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat. |
 Anti-TFIIIB90-1 Antibody |
|
A03761-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for TFIIIB90-1 Antibody (BRF1) detection.tested for WB in Human, Mouse. |
 Anti-Atrophin-1 Antibody |
|
A03828-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for Atrophin-1 Antibody (ATN1) detection. Tested with WB in Human, Mouse, Rat. |
 Anti-CNG-1 Antibody |
|
A05494-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for CNG-1 Antibody (CNGA1) detection. Tested with WB in Human, Mouse, Rat. |
 Anti-Periphilin 1 Antibody |
|
A06996-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for Periphilin 1 Antibody (PPHLN1) detection.tested for WB in Human, Mouse. |
 Anti-Lyl-1 Antibody |
|
A07491-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Lyl-1 Antibody. Validated in IHC and tested in Human, Mouse, Rat. |
 Anti-GLI-1 Antibody |
|
A07972-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for GLI-1 Antibody (ACSS1) detection. Tested with WB in Human, Mouse, Rat. |
 Anti-Cerebellin 1 Antibody |
|
A09176-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for Cerebellin 1 Antibody (CBLN1) detection. Tested with WB in Human, Mouse, Rat. |
 Anti-DOC-1 Antibody |
|
A09467-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for DOC-1 Antibody (CDK2AP1) detection. Tested with WB in Human, Mouse. |
 Anti-Bag-1 Antibody |
|
A02423-1 |
BosterBio |
50 ul |
EUR 397 |
|
Description: Rabbit Polyclonal Bag-1 Antibody. Validated in IP, IHC and tested in Bovine, Canine, Human, Mouse, Rat. |
 Anti-TUB 1 Antibody |
|
A02917-1 |
BosterBio |
100ug/vial |
EUR 294 |
 Anti-Dok-1 Antibody |
|
A03039-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for Dok-1 Antibody (DOK1) detection.tested for WB in Human, Mouse, Rat. |
 Anti-NPDC-1 Antibody |
|
A12846-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for NPDC-1 Antibody (NPDC1) detection. Tested with WB in Human, Mouse, Rat. |
 Rabbit Anti-Human FLT-4/VEGFR-3 IgG #2, aff pure |
|
FLT42-A |
Alpha Diagnostics |
100 ug |
EUR 482 |
 Monoclonal Antibody (2E12)) Anti-Apaf-1 (human) Monoclonal Antibody (2E12) |
|
M00889-1 |
BosterBio |
100ug |
EUR 432 |
|
Description: Rat Monoclonal Apaf-1 (human) Antibody (2E12). Validated in ELISA, IP, IF, WB and tested in Human. |
) Anti-HO-1 Monoclonal Antibody (HO-1-2) |
|
M00253-1 |
BosterBio |
1mg |
EUR 397 |
|
Description: Mouse Monoclonal HO-1 Antibody (HO-1-2). Validated in Flow Cytometry, IHC, WB and tested in Human, Mouse, Rat. |
 Anti-Esrp-1 Monoclonal Antibody |
|
M06068-1 |
BosterBio |
100uL |
EUR 443 |
|
Description: Mouse Monoclonal Esrp-1 Antibody. Validated in WB and tested in Human. |
 Anti-Presenilin 1 Monoclonal Antibody |
|
M00138-1 |
BosterBio |
100ug |
EUR 397 |
|
Description: Rabbit Monoclonal Presenilin 1 Antibody. Validated in WB and tested in Human, Mouse, Rat. |
 Anti-Galectin 1 Monoclonal Antibody |
|
M00470-1 |
BosterBio |
100ug |
EUR 397 |
|
Description: Rabbit Monoclonal Galectin 1 Antibody. Validated in IP, IF, WB and tested in Human, Mouse, Rat. |
 Anti-DJ-1 Monoclonal Antibody |
|
M00757-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Mouse Monoclonal DJ-1 Antibody. Validated in IHC, WB and tested in Bovine, Human. |
 Anti-Enolase 1 Monoclonal Antibody |
|
M01250-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Anti-Enolase 1 Monoclonal Antibody tested in WB, IF, ICC, IHC, reactive to Human, rat, mouse, cow, pig, horse |
 Anti-Dynamin 1 Monoclonal Antibody |
|
M02536-1 |
BosterBio |
100ug |
EUR 397 |
|
Description: Rabbit Monoclonal Dynamin 1 Antibody. Validated in IF, WB and tested in Human, Mouse, Rat. |
 Anti-Angiopoietin 1/ANGPT1 Antibody |
|
PA1333-1 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-Galectin 1/LGALS1 Antibody |
|
PB9240-1 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-TNF Receptor 1 Antibody |
|
A00294-1 |
BosterBio |
200ug |
EUR 522 |
|
Description: Rabbit Polyclonal TNF Receptor 1 Antibody. Validated in IP, IHC, WB and tested in Human, Mouse, Rat. |
 Anti-Galectin 1/Lgals1 Antibody |
|
A00470-1 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-LOX-1/OLR1 Antibody |
|
A00760-1 |
BosterBio |
100ug/vial |
EUR 294 |
 Anti-Syndecan-1/SDC1 Antibody |
|
A00991-1 |
BosterBio |
100ug/vial |
EUR 294 |
 Anti-IRAK-1/IRAK1 Antibody |
|
A01021-1 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-Neurexin 1/NRXN1 Antibody |
|
A01490-1 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-Hexokinase 1/HK1 Antibody |
|
A01504-1 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-Musashi 1/Msi1 Antibody |
|
A05052-1 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-Pyrophosphatase 1/PPA1 Antibody |
|
A07485-1 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-TCP-1 eta Antibody |
|
A08169-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for TCP-1 eta Antibody (CCT7) detection. Tested with WB in Human, Mouse, Rat. |
 Anti-Relaxin 1/RLN1 Antibody |
|
A08367-1 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-TCP-1 zeta Antibody |
|
A09373-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for TCP-1 zeta Antibody (CCT6A) detection.tested for WB in Human, Mouse, Rat. |
 Anti-Synaptotagmin 1/SYT1 Antibody |
|
A02314-1 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-Syntenin-1 Monoclonal Antibody |
|
A02475-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Mouse Monoclonal Antibody for Syntenin-1 Antibody (SDCBP) detection. Tested with WB in Human, Rat, Dog, Pig. |
 Anti-Dsg1/Desmoglein 1 Antibody |
|
A02655-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for Dsg1 Antibody (DSG1) detection.tested for IHC, WB in Human, Mouse, Rat. |
 Anti-CAF-1 p150 Antibody |
|
A02732-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for CAF-1 p150 Antibody (CHAF1A) detection. Tested with WB in Human, Mouse. |
 Anti-Talin 1/TLN1 Antibody |
|
A02859-1 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-Islet 1/ISL1 Antibody |
|
A02969-1 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-CHST8/Galnac4St 1 Antibody |
|
A10989-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal CHST8/Galnac4St 1 Antibody. Validated in WB and tested in Human, Mouse, Rat. |
 VEGFR-1 Antibody |
|
48347-100ul |
SAB |
100ul |
EUR 333 |
VEGFR-1 Antibody |
|
48347-50ul |
SAB |
50ul |
EUR 239 |
 Monoclonal Antibody (JSB-1)) Anti-P-glycoprotein (human) Monoclonal Antibody (JSB-1) |
|
M00049-1 |
BosterBio |
125ug |
EUR 586 |
|
Description: Mouse Monoclonal P-glycoprotein (human) Antibody (JSB-1). Validated in IF and tested in Human. |
 Human FLT-4/VEGFR-3 control/blocking peptide #2 |
|
FLT42-P |
Alpha Diagnostics |
100 ug |
EUR 164 |
 Anti-BOB-1/OBF-1 Rabbit Monoclonal Antibody, Clone#RM378 |
|
M04431-1 |
BosterBio |
100uL |
EUR 385 |
|
Description: Anti-BOB-1/OBF-1 Rabbit Monoclonal Antibody, Clone#RM378 tested in WB, IHC, reactive to Human |
 AXMIR-1 RNA oligo anti-miRNA-1-3p with Xmotif |
|
AXMIR-1 |
SBI |
10 reactions |
EUR 438 |
|
|
 Anti-Sumo 1 Rabbit Monoclonal Antibody |
|
M00631-1 |
BosterBio |
100ug/vial |
EUR 397 |
|
Description: Rabbit Monoclonal Sumo 1 Antibody. Validated in IP, IF, IHC, WB and tested in Human, Mouse, Rat. |
 Anti-Cytokeratin 1 Rabbit Monoclonal Antibody |
|
M01639-1 |
BosterBio |
100ug/vial |
EUR 397 |
|
Description: Rabbit Monoclonal Cytokeratin 1 Antibody. Validated in WB and tested in Human, Mouse, Rat. |
) Anti-Mitofusin 1 Antibody (monoclonal, 3H3) |
|
M02172-1 |
BosterBio |
100ug/vial |
EUR 294 |
 Antibody) Anti-Phospho-Beclin-1 (Ser295) Antibody |
|
P00327-1 |
BosterBio |
100ul |
EUR 398 |
|
Description: Rabbit Polyclonal Phospho-Beclin-1 (Ser295) Antibody. Validated in WB and tested in Human. |
 Antibody) Anti-Phospho-Raf-1 (Ser642) Antibody |
|
P00446-1 |
BosterBio |
100ul |
EUR 398 |
|
Description: Rabbit Polyclonal Phospho-Raf-1 (Ser642) Antibody. Validated in WB and tested in Human, Rat. |
 Anti-Integrin alpha 1/ITGA1 Antibody |
|
PA1045-1 |
BosterBio |
100ug/vial |
EUR 334 |
/CASP1 Antibody) Anti-Caspase-1(P20)/CASP1 Antibody |
|
PA1440-1 |
BosterBio |
100ug/vial |
EUR 294 |
 Anti-VEGF Receptor 1/FLT1 Antibody |
|
PA1966-1 |
BosterBio |
100ug/vial |
EUR 294 |
 Anti-HIF-1 alpha/HIF1A Antibody |
|
A00013-1 |
BosterBio |
100ug/vial |
EUR 294 |
 Antibody) Anti-Cleaved-Notch 1 (V1754) Antibody |
|
A00033-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for Cleaved-Notch 1 (V1754) Antibody (NOTCH1) detection.tested for WB in Human, Mouse, Rat. |
 Antibody) Anti-HDAC-1 (C-terminus) Antibody |
|
A00256-1 |
BosterBio |
100uL |
EUR 443 |
|
Description: Rabbit Polyclonal HDAC-1 (C-terminus) Antibody. Validated in IF, IHC, WB and tested in Human. |
Anti-VEGF Receptor 1/FLT1 Antibody |
|
A00534-1 |
BosterBio |
100ug/vial |
EUR 294 |
 Anti-Liver Carboxylesterase 1/CES1 Antibody |
|
A01741-1 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-Hyaluronan synthase 1/HAS1 Antibody |
|
A04784-1 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-CELSR3/Flamingo Homolog 1 Antibody |
|
A07204-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal CELSR3/Flamingo Homolog 1 Antibody. Validated in IF and tested in Human, Mouse, Rat. |
 Anti-LPCAT2/Acyltransferase Like 1 Antibody |
|
A07471-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal LPCAT2/Acyltransferase Like 1 Antibody. Validated in WB and tested in Human, Mouse, Rat. |
 Anti-EBP50/NHERF-1/SLC9A3R1 Antibody |
|
A02427-1 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-IL1R2/Il 1 Rii Antibody |
|
A03106-1 |
BosterBio |
1 ml |
EUR 397 |
|
Description: Rabbit Polyclonal IL1R2/Il 1 Rii Antibody. Validated in IP, WB and tested in Human. |
 Anti-TTF-1 |
|
DB-089-1 |
DB Biotech |
1 ml |
EUR 750 |
|
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
 Monoclonal Antibody (MEM-G/1)) Anti-HLA-G (human) Monoclonal Antibody (MEM-G/1) |
|
M01235-1 |
BosterBio |
100ug |
EUR 397 |
|
Description: Mouse Monoclonal HLA-G (human) Antibody (MEM-G/1). Validated in IHC, WB and tested in Human. |
 antibody) Anti-Phospho-Flt-1 (Y1048) antibody |
|
STJ91223 |
St John's Laboratory |
200 µl |
EUR 197 |
|
Description: Rabbit polyclonal to Phospho-Flt-1 (Y1048). |
 antibody) Anti-Phospho-Flt-1 (Y1213) antibody |
|
STJ91359 |
St John's Laboratory |
200 µl |
EUR 197 |
|
Description: Rabbit polyclonal to Phospho-Flt-1 (Y1213). |
 Anti-Flk-1/Flt-4 antibody |
|
STJ93091 |
St John's Laboratory |
200 µl |
EUR 197 |
|
Description: Rabbit polyclonal to Flk-1/Flt-4. |
 antibody) Anti-Phospho-Flt-1 (Y1333) antibody |
|
STJ90838 |
St John's Laboratory |
200 µl |
EUR 197 |
|
Description: Rabbit polyclonal to Phospho-Flt-1 (Y1333). |
, amide, human) Endothelin-1 (1-15), amide, human |
|
A1111-1 |
ApexBio |
1 mg |
EUR 722 |
|
Description: Endothelins are 21-amino acid vasoconstricting peptides produced primarily in the endothelium and have a key role in vascular homeostasis. |
 Human Plasma) Haptoglobin, (Phenotype 1-1) Human Plasma |
|
7536-1 |
Biovision |
|
EUR 321 |
) Hemokinin 1 (human) |
|
B5318-1 |
ApexBio |
1 mg |
EUR 340 |
) Anti-Musashi 1/Msi1 Antibody (monoclonal, 2B9) |
|
M05052-1 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-Visinin-like Protein 1 Monoclonal Antibody |
|
M06959-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Mouse Monoclonal Visinin-like Protein 1 Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat. |
 Anti-HMGB1/Hmg 1 Rabbit Monoclonal Antibody |
|
M00066-1 |
BosterBio |
100ug/vial |
EUR 397 |
|
Description: Rabbit Monoclonal HMGB1/Hmg 1 Antibody. Validated in Flow Cytometry, IF, IHC, ICC, WB and tested in Human, Mouse, Rat. |
 Anti-p27 KIP 1 Rabbit Monoclonal Antibody |
|
M00173-1 |
BosterBio |
100ug/vial |
EUR 397 |
|
Description: Anti-p27 KIP 1 Rabbit Monoclonal Antibody tested for Flow Cytometry, IP, IF, IHC, ICC, WB in Human, Rat |
) Anti-Caveolin-1/CAV1 Antibody (monoclonal, 12C7) |
|
M00179-1 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-MHC class 1 Rabbit Monoclonal Antibody |
|
M00194-1 |
BosterBio |
100ug/vial |
EUR 397 |
|
Description: Rabbit Monoclonal MHC class 1 Antibody. Validated in IP, IF, IHC, WB and tested in Human. |
 Anti-Integrin beta 1 Rabbit Monoclonal Antibody |
|
M00772-1 |
BosterBio |
100ug/vial |
EUR 397 |
|
Description: Rabbit Monoclonal Integrin beta 1 Antibody. Validated in IHC, WB and tested in Human, Mouse, Rat. |
 Anti-ARG1/Arginase 1 Rabbit Monoclonal Antibody |
|
M01106-1 |
BosterBio |
100ug/vial |
EUR 397 |
|
Description: Rabbit Monoclonal ARG1/Arginase 1 Antibody. Validated in IP, WB and tested in Human, Mouse, Rat. |
 Anti-MLANA/Mart 1 Rabbit Monoclonal Antibody |
|
M02033-1 |
BosterBio |
100ug/vial |
EUR 397 |
|
Description: Rabbit Monoclonal MLANA/Mart 1 Antibody. Validated in IF, WB and tested in Human. |
) Anti-TCP-1α Monoclonal Antibody (91a) |
|
M02389-1 |
BosterBio |
200ug |
EUR 498 |
|
Description: Rat Monoclonal TCP-1α Antibody (91a). Validated in Flow Cytometry, IP, IF, WB and tested in Human, Mouse, Rat. |
 Anti-DSG1/Desmoglein 1 Rabbit Monoclonal Antibody |
|
M02655-1 |
BosterBio |
100ug/vial |
EUR 397 |
|
Description: Rabbit Monoclonal DSG1/Desmoglein 1 Antibody. Validated in IF, IHC, ICC, WB and tested in Human, Mouse, Rat. |
 Antibody) Anti-Phospho-Glycogen Synthase 1 (S645) Antibody |
|
P03512-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for Phospho-Glycogen Synthase 1 (S645) Antibody (GYS1) detection.tested for WB in Human, Mouse, Rat. |
 Anti-Angiotensin Converting Enzyme 1/ACE Antibody |
|
PA2196-1 |
BosterBio |
100ug/vial |
EUR 334 |
 Anti-GABA B Receptor 1/GABBR1 Antibody |
|
A07297-1 |
BosterBio |
100ug/vial |
EUR 294 |
 Anti-Vangl1/Vang Like Protein 1 Antibody |
|
A07587-1 |
BosterBio |
100ul |
EUR 397 |
|
Description: Rabbit Polyclonal Antibody for Vangl1 Antibody (VANGL1) detection. Tested with WB in Human, Mouse. |
 Anti-E74 like factor 1/ELF1 Antibody |
|
A03187-1 |
BosterBio |
100ug/vial |
EUR 294 |
, human recombinant protein) Neuregulin/Heregulin-1? (NRG-1?/HRG-1?), human recombinant protein |
|
P1054-1 |
ApexBio |
1 mg |
EUR 3947 |
|
Description: Neuregulin (NRG) is a signaling protein for ErbB2/ErbB4 receptor heterodimers on the cardiac muscle cells and plays an important role in heart structure and function through inducing cardiomyocyte differentiation |
 miRZip-1 anti-miR-1 microRNA construct |
|
MZIP1-PA-1 |
SBI |
Bacterial Streak |
EUR 684 |
|
|
 Anti-EBV/LMP-1 |
|
DB-060-1 |
DB Biotech |
1 ml |
EUR 750 |
|
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
Anti-EBV/LMP-1 |
|
DB-061-1 |
DB Biotech |
1 ml |
EUR 750 |
|
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
 MMP-1 Matrix Metalloproteinase-1 Human Recombinant Protein |
|
PROTP03956-1 |
BosterBio |
Regular: 20ug |
EUR 317 |
|
Description: MMP 1 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 393 amino acids (100-469a.a) and having a molecular mass of 45kDa. MMP 1 is fused to a 23 amino acid His-tag at N-terminus. |
 Anti-AFP/Alpha 1 Fetoprotein Rabbit Monoclonal Antibody |
|
M00522-1 |
BosterBio |
100ug/vial |
EUR 397 |
|
Description: Rabbit Monoclonal AFP/Alpha 1 Fetoprotein Antibody. Validated in IP, IF, WB and tested in Human. |
 Anti-SERPINA1/Alpha 1 Antitrypsin Rabbit Monoclonal Antibody |
|
M00720-1 |
BosterBio |
100ug/vial |
EUR 397 |
|
Description: Rabbit Monoclonal SERPINA1/Alpha 1 Antitrypsin Antibody. Validated in IP, IF, WB and tested in Human. |
 Anti-GPX1/Glutathione Peroxidase 1 Rabbit Monoclonal Antibody |
|
M01019-1 |
BosterBio |
100ug/vial |
EUR 397 |
|
Description: Rabbit Monoclonal GPX1/Glutathione Peroxidase 1 Antibody. Validated in IP, WB and tested in Human, Mouse, Rat. |
 Anti-BAG-1 Rabbit Monoclonal Antibody, Clone#RM356 |
|
M02423-1 |
BosterBio |
100uL |
EUR 385 |
|
Description: Anti-BAG-1 Rabbit Monoclonal Antibody, Clone#RM356 tested in WB, IHC, reactive to Human |
 Anti-Mitochondrial Pyruvate dehydrogenase kinase 1/PDK1 Antibody |
|
A01268-1 |
BosterBio |
100ug/vial |
EUR 334 |
 XStamp Pro anti-PD-1 EV Targeting Kit |
|
XSTP915A-1 |
SBI |
10 rxn |
EUR 805 |
|
|
 IGF-1, human recombinant |
|
P1016-.1 |
ApexBio |
100 µg |
EUR 763 |
|
Description: Insulin-like growth factor I (IGF-1) is a polypeptide endocrine hormone structurally similar to insulin and is mainly produced in the liver when stimulated by growth hormone. IGF-1 is a growth factor that stimulates the proliferation of various cell types including muscle, bone, and cartilage tissue |
, human) BNP (1-32), human |
|
A1105-1 |
ApexBio |
1 mg |
EUR 177 |
|
Description: Basic natriuretic peptide (BNP), now known as B-type natriuretic peptide (also BNP) or GC-B, is a 32 amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes). |
 RAD51D (1-328 a.a.) Human Recombinant Protein) (1-328) RAD51D (1-328 a.a.) Human Recombinant Protein |
|
PROTO75771-1 |
BosterBio |
Regular: 10ug |
EUR 317 |
|
Description: RAD51D (1-328) Human Recombinant produced in E. coli is. a single polypeptide chain containing 351 amino acids and having a molecular mass of 37.4kDa. RAD51D (1-328) is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
 IL1RL1 Human, Interleukin-1 Receptor Like-1 Human Recombinant Protein, Sf9 |
|
PROTQ01638-1 |
BosterBio |
Regular: 10ug |
EUR 317 |
|
Description: IL 1RL1 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain (19-328 a.a.) and fused to an 8 aa His Tag at C-terminus containing a total of 318 amino acids and having a molecular mass of 36.0kDa.;IL 1RL1 shows multiple bands between 40-57kDa on SDS-PAGE, reducing conditions and purified by proprietary chromatographic techniques. |
 Rabbit Monoclonal Antibody) Anti-Phospho-AMPK alpha 1 (S496) Rabbit Monoclonal Antibody |
|
P00994-1 |
BosterBio |
100ug/vial |
EUR 397 |
|
Description: Rabbit Monoclonal Phospho-AMPK alpha 1 (S496) Antibody. Validated in IP, IF, WB and tested in Human. |
, 2mg/mL) CF350 Goat Anti-Mouse IgG1 (γ1), 2mg/mL |
|
20245-1 |
Biotium |
50uL |
EUR 149 |
|
Description: Minimum order quantity: 1 unit of 50uL |
, 2mg/mL) CF488A Goat Anti-Mouse IgG1 (γ1), 2mg/mL |
|
20246-1 |
Biotium |
50uL |
EUR 149 |
|
Description: Minimum order quantity: 1 unit of 50uL |
, 2mg/mL) CF555 Goat Anti-Mouse IgG1 (γ1), 2mg/mL |
|
20247-1 |
Biotium |
50uL |
EUR 149 |
|
Description: Minimum order quantity: 1 unit of 50uL |
, 2mg/mL) CF568 Goat Anti-Mouse IgG1 (γ1), 2mg/mL |
|
20248-1 |
Biotium |
50uL |
EUR 149 |
|
Description: Minimum order quantity: 1 unit of 50uL |
, 2mg/mL) CF594 Goat Anti-Mouse IgG1 (γ1), 2mg/mL |
|
20249-1 |
Biotium |
50uL |
EUR 149 |
|
Description: Minimum order quantity: 1 unit of 50uL |
, 2mg/mL) CF633 Goat Anti-Mouse IgG1 (γ1), 2mg/mL |
|
20250-1 |
Biotium |
50uL |
EUR 149 |
|
Description: Minimum order quantity: 1 unit of 50uL |
, 2mg/mL) CF640R Goat Anti-Mouse IgG1 (γ1), 2mg/mL |
|
20251-1 |
Biotium |
50uL |
EUR 149 |
|
Description: Minimum order quantity: 1 unit of 50uL |
, 2mg/mL) CF647 Goat Anti-Mouse IgG1 (γ1), 2mg/mL |
|
20252-1 |
Biotium |
50uL |
EUR 149 |
|
Description: Minimum order quantity: 1 unit of 50uL |
, 2mg/mL) CF680 Goat Anti-Mouse IgG1 (γ1), 2mg/mL |
|
20253-1 |
Biotium |
50uL |
EUR 161 |
|
Description: Minimum order quantity: 1 unit of 50uL |
, 2mg/mL) CF770 Goat Anti-Mouse IgG1 (γ1), 2mg/mL |
|
20254-1 |
Biotium |
50uL |
EUR 161 |
|
Description: Minimum order quantity: 1 unit of 50uL |
, 2mg/mL) CF543 Goat Anti-Mouse IgG1 (γ1), 2mg/mL |
|
20325-1 |
Biotium |
50uL |
EUR 149 |
|
Description: Minimum order quantity: 1 unit of 50uL |
 Flt-1 Polyclonal Antibody |
|
ES5317-50ul |
ELK Biotech |
50ul |
EUR 207 |
|
Description: A Rabbit Polyclonal antibody against Flt-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
Flt-1 Polyclonal Antibody |
|
ES5318-100ul |
ELK Biotech |
100ul |
EUR 279 |
|
Description: A Rabbit Polyclonal antibody against Flt-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
Flt-1 Polyclonal Antibody |
|
ES5317-100ul |
ELK Biotech |
100ul |
EUR 279 |
|
Description: A Rabbit Polyclonal antibody against Flt-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
Flt-1 Polyclonal Antibody |
|
ES5318-50ul |
ELK Biotech |
50ul |
EUR 207 |
|
Description: A Rabbit Polyclonal antibody against Flt-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
Flt-1 Polyclonal Antibody |
|
ABP54318-003ml |
Abbkine |
0.03ml |
EUR 158 |
|
|
|
Description: A polyclonal antibody for detection of Flt-1 from Human, Mouse, Rat. This Flt-1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Flt-1 around the non-phosphorylation site of Y1048 |
Flt-1 Polyclonal Antibody |
|
ABP54318-01ml |
Abbkine |
0.1ml |
EUR 289 |
|
|
|
Description: A polyclonal antibody for detection of Flt-1 from Human, Mouse, Rat. This Flt-1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Flt-1 around the non-phosphorylation site of Y1048 |
Flt-1 Polyclonal Antibody |
|
ABP54318-02ml |
Abbkine |
0.2ml |
EUR 414 |
|
|
|
Description: A polyclonal antibody for detection of Flt-1 from Human, Mouse, Rat. This Flt-1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Flt-1 around the non-phosphorylation site of Y1048 |
Flt-1 Polyclonal Antibody |
|
ABP54319-003ml |
Abbkine |
0.03ml |
EUR 158 |
|
|
|
Description: A polyclonal antibody for detection of Flt-1 from Human, Mouse, Rat. This Flt-1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Flt-1 around the non-phosphorylation site of Y1333 |
Flt-1 Polyclonal Antibody |
|
ABP54319-01ml |
Abbkine |
0.1ml |
EUR 289 |
|
|
|
Description: A polyclonal antibody for detection of Flt-1 from Human, Mouse, Rat. This Flt-1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Flt-1 around the non-phosphorylation site of Y1333 |
Flt-1 Polyclonal Antibody |
|
ABP54319-02ml |
Abbkine |
0.2ml |
EUR 414 |
|
|
|
Description: A polyclonal antibody for detection of Flt-1 from Human, Mouse, Rat. This Flt-1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Flt-1 around the non-phosphorylation site of Y1333 |
) Anti-EMA (CD227, Mucin-1) |
|
DB-048-1 |
DB Biotech |
1 ml |
EUR 450 |
|
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
 PSG1 Human, Pregnancy Specific Beta-1-Glycoprotein 1 Human Recombinant Protein, Sf9 |
|
PROTP11464-1 |
BosterBio |
Regular: 10ug |
EUR 317 |
|
Description: PSG1 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 394 amino acids (35-419a.a.) and having a molecular mass of 44.6kDa (Molecular size on SDS-PAGE will appear at approximately 40-57kDa). PSG1 is expressed with a 6 amino acids His tag at C-Terminus and purified by proprietary chromatographic techniques. |
 GAD1 iso1 Glutamate Decarboxylase 1 Isoform-1 Human Recombinant Protein |
|
PROTQ99259-1 |
BosterBio |
Regular: 20ug |
EUR 317 |
|
Description: GAD1 iso1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 617 amino acids (1-594 a.a) and having a molecular mass of 69.3kDa. GAD1 iso1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
 TGF-b-1 Transforming Growth Factor-beta 1 Human protein |
|
PROTP01137-1 |
BosterBio |
Regular: 2.5ug |
EUR 1157 |
|
Description: Human Transforming Growth Factor-beta 1 purified from Human Platelets having a molecular mass of 25kDa.;The TGF-b 1 is purified by proprietary chromatographic techniques. |
) MCP-1 Monocyte Chemotactic Protein-1 Human Recombinant Protein (CCL2) |
|
PROTP13500-1 |
BosterBio |
Regular: 20ug |
EUR 317 |
|
Description: Monocyte Chemotactic Protein-1 Human Recombinant also known as Monocyte Chemotactic and Activating Factor (MCAF) produced in E.Coli is a non-glycosylated, Polypeptide chain containing 76 amino acids and having a molecular mass of 8.6kDa. ;The MCP-1 is purified by proprietary chromatographic techniques. |
 AssayMax ELISA Kit) Human Interleukin-1 beta (IL-1 beta) AssayMax ELISA Kit |
|
EI2200-1 |
AssayPro |
96 Well Plate |
EUR 477 |
 AssayMax ELISA Kit) Human Interleukin-1-alpha (IL-1-alpha) AssayMax ELISA Kit |
|
EI2301-1 |
AssayPro |
96 Well Plate |
EUR 477 |
 AssayMax ELISA Kit) Human KRAB-associated Protein 1 (KAP-1) AssayMax ELISA Kit |
|
EK2802-1 |
AssayPro |
96 Well Plate |
EUR 477 |
 AssayMax ELISA Kit) Human Plasminogen Activator Inhibitor-1 (PAI-1) AssayMax ELISA Kit |
|
EP1100-1 |
AssayPro |
96 Well Plate |
EUR 417 |
 Recombinant Human ANG-1 Protein |
|
PROTQ15389-1 |
BosterBio |
20ug |
EUR 317 |
|
Description: Angiopoietin-1 (Ang-1) is a secreted ligand for Tie-2, a tyrosine-kinase receptor expressed primarily on vascular endothelial cells and early hematopoietic cells. Ang-1/ Tie-2 signaling promotes angiogenesis during the development, remodeling, and repair of the vascular system. Transgenic mice lacking expression of either Ang-1 or Tie-2 fail to develop a fully functional cardiovascular system and die before birth. Postnatally, the angiogenic activity of Ang-1/Tie-2 is required during normal tissue repair and remodeling of the female endometrium in the menstrual cycle. Ang-1/Tie-2 signaling appears to be regulated by Angiopoietin-2 (Ang-2), a natural antagonist for Tie-2 that exerts its effects through an internal autocrine loop mechanism. In addition to suppressing endothelial cell activation by inhibiting the expression of adhesion and inflammatory molecules, Ang-1 enhances endothelial cell survival and capillary morphogenesis, and lessens capillary permeability. As such, Ang-1 has a potential to become an effective therapeutic agent for treating various endothelium disorders, including several severe human pulmonary diseases. The efficacy of cell-based Ang-1 gene therapy for acute lung injury (ALI) has recently been studied in a rat model of ALI (1). The results of this study show that such therapy can markedly improve lung condition and suggest that Ang-1 therapy may represent a potential new strategy for the treatment and/or prevention of acute respiratory distress injury (ARDI), a significant cause of morbidity and mortality in critically ill patients. Recombinant human ANG-1, derived from HeLa cells, is a C-terminal histidine tagged glycoprotein which migrates with an apparent molecular mass of 60.0 – 70.0 kDa by SDS-PAGE under reducing conditions. Sequencing analysis shows N-terminal sequences starting with Ser-20 and with Asp-70 of the 498 amino acid precursor protein. |
 ORM1 Orosomucoid 1 Human protein |
|
PROTP02763-1 |
BosterBio |
Regular: 10ug |
EUR 317 |
|
Description: The Human Orosomucoid 1 produced from Human pooled serum has a molecular mass of 21.56kDa (calculated without glycosylation) containing 183 amino acid residues. |
 Recombinant Human Galectin-1 Protein |
|
PROTP09382-1 |
BosterBio |
50ug |
EUR 317 |
|
Description: Lectins, of either plant or animal origin, are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with β-galactoside moieties. Galectin-1 is an animal lectin that has been shown to interact with CD3, CD4, and CD45. It induces apoptosis of activated T-cells and T-leukemia cell lines and inhibits the protein phosphatase activity of CD45. Recombinant human Galectin-1 is a 14.5 kDa protein containing 134 amino acid residues. |
 Recombinant Human PECAM-1 Protein |
|
PROTP16284-1 |
BosterBio |
50ug |
EUR 317 |
|
Description: PECAM is transmembrane glycoprotein that belongs to the Ig-related superfamily of adhesion molecules. It is highly expressed at endothelial cell junctions, and also expressed in platelets and in most leukocyte sub-types. The primary function of PECAM-1 is the mediation of leukocyte-endothelial cell adhesion and signal transduction. PECAM-1 has been implicated in the pathogenesis of various inflammation related disorders, including thrombosis, multiple sclerosis (MS), and rheumatoid arthritis. The human PECAM-1 gene codes for a 738 amino acid transmembrane glycoprotein containing a 118 amino acid cytoplasmic domain, a 19 amino acid transmembrane domain, and a 574 amino acid extracellular domain. Recombinant human PECAM-1 is a 572 amino acid glycoprotein comprising the extracellular domain of PECAM-1. Monomeric glycosylated PECAM-1 migrates at an apparent molecular weight of approximately 80.0-95.0 kDa by SDS-PAGE analysis under reducing conditions |
 Recombinant Human Gremlin-1 Protein |
|
PROTO60565-1 |
BosterBio |
50ug |
EUR 317 |
|
Description: Gremlin-1 (isoform-1) belongs to a group of diffusible proteins which bind to ligands of the TGF-β family and regulate their activity by inhibiting their access to signaling receptors. The interplay between TGF-β ligands and their natural antagonists has major biological significance during development processes, in which cellular response can vary considerably depending upon the local concentration of the signaling molecule. Gremlin is highly expressed in the small intestine, fetal brain, and colon and lower expression in brain, prostate, pancreas and skeletal muscle. Gremlin-1 regulates multiple functions in early development by specifically binding to and inhibiting the function of BMP-2, -4, and -7. It also plays a role in carcinogenesis and kidney branching morphogenesis. Recombinant Gremlin-1 is a 18.3 kDa protein containing 160 amino acid residues. |
Our outcomes help the speculation that cucurbit permutations had been in all probability pushed by elevated genetic variety following polyploidizations and by trait morphological improvements below paleo-climate upheavals. Our examine gives a phylogenetic framework and new insights into morphological and genomic changes underlying the adaptive evolution of Cucurbitaceae.
